Table 1.
Patient characteristics at baseline
| TXA (n = 101) | Placebo (n = 101) | |
|---|---|---|
| Age (years)* | 66·2(13·3) | 62·3(12·8)‡ |
| Women | 98 (97·0) | 100 (99·0) |
| BMI (kg/m2)* | 26·9(4·9) | 27·1(4·7) |
| Active smoker | 19 (18·8) | 13 (12·9) |
| Recruited at centre A | 77 (76·2) | 77 (76·2) |
| Operated on by senior surgeon | 50 (49·5) | 50 (49·5) |
| Neoadjuvant treatment | 32 (31·7) | 41 (40·6) |
| Irradiated tissue | 14 (13·9) | 11 (10·9) |
| Perioperative anticoagulation | 32 (31·7) | 37 (36·6) |
| Axillary clearance | 34 (33·7) | 31 (30·7) |
| Weight of breast specimen (g)*, † | 780(450) | 746(359) |
| Wound surface area (cm2)*, † | 292(117) | 279(84) |
Values in parentheses are percentages unless indicated otherwise;
*
values are mean(s.d.)
†
Axillary component included. TXA, tranexamic acid.
‡
P = 0·033 versus TXA (independent‐samples t test).