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. 2020 Feb 6;35:100958. doi: 10.1016/j.molmet.2020.02.001

Figure 5.

Figure 5

Reduced β-cell Mass Expansion in S961-Treated βKlf6KO Mice. (a) Quantification of Ki67-positive β-cells over islet cell surface in mice treated with saline or S961 for 7 days (n = 5–7). (b) β-cell mass in response to saline and S961 treatment. (c) Islet density and (d) size distribution of islets following S961 treatment for 7 days (n = 4–5). Statistical analyses were performed using a two-way ANOVA (Bonferonni's post-hoc test) ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001. Error bars represent SEM.