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. 2014 Nov 21;2014(11):CD002745. doi: 10.1002/14651858.CD002745.pub4

Comparison 3. Amantadine and rimantadine compared to placebo in the prophylaxis of influenza A in the elderly.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 RMT (proved and clinical infection) 3 191 Risk Ratio (M‐H, Random, 95% CI) 0.74 [0.13, 4.07]
2 RMT Monto (100 + 200) and Patriarca 2 103 Risk Ratio (M‐H, Random, 95% CI) 0.45 [0.14, 1.41]
3 RMT 200 2 75 Risk Ratio (M‐H, Random, 95% CI) 0.44 [0.12, 1.63]
4 RMT 100 2 130 Risk Ratio (M‐H, Random, 95% CI) 1.42 [0.10, 21.10]