Comparison 8. Adverse effects related to different doses of rimantadine in the elderly.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Confusion	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.83 [0.41, 1.65]
1.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.83 [0.41, 1.65]
2 Depression	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.44 [0.12, 1.65]
2.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.44 [0.12, 1.65]
3 Impaired concentration	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.68 [0.11, 3.98]
3.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.68 [0.11, 3.98]
4 Insomnia or sleeplessness	1	262	Risk Ratio (M‐H, Random, 95% CI)	1.02 [0.26, 3.97]
4.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	1.02 [0.26, 3.97]
5 Loss of appetite	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.62 [0.27, 1.46]
5.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.62 [0.27, 1.46]
6 Rash or allergic reaction	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.34 [0.04, 3.21]
6.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.34 [0.04, 3.21]
7 Seizure or clonic twitching	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.11 [0.01, 2.07]
7.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.11 [0.01, 2.07]
8 Dry mouth	1	262	Risk Ratio (M‐H, Random, 95% CI)	1.16 [0.43, 3.11]
8.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	1.16 [0.43, 3.11]
9 Fatigue and drowsiness	1	262	Risk Ratio (M‐H, Random, 95% CI)	1.14 [0.45, 2.87]
9.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	1.14 [0.45, 2.87]
10 Headache	1	262	Risk Ratio (M‐H, Random, 95% CI)	1.02 [0.30, 3.42]
10.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	1.02 [0.30, 3.42]
11 Body weakness or debility	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.91 [0.38, 2.18]
11.1 RMT	1	262	Risk Ratio (M‐H, Random, 95% CI)	0.91 [0.38, 2.18]