| Methods |
Randomised double‐blind placebo‐controlled trial |
| Participants |
Depressed inpatients aged 6‐12 years
Gender unknown
13 active treatment, 14 placebo
4 withdrawals |
| Interventions |
Imipramine. Dose not stated |
| Outcomes |
Children's Depression Rating Scale
Follow‐up interval 6 weeks |
| Notes |
Study quality score = 18 |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
High risk |
Not stated |
| Allocation concealment (selection bias) |
High risk |
|
| Blinding (performance bias and detection bias)
of participants |
Unclear risk |
No description was provided |
| Blinding (performance bias and detection bias)
of personnel |
Unclear risk |
No description was provided |
| Blinding (performance bias and detection bias)
of outcome assessors |
Unclear risk |
No description was provided |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Numbers and reasons for withdrawals were provided but analysis was not modified |
| Selective reporting (reporting bias) |
Unclear risk |
‐ |
| Other bias |
Unclear risk |
Previous or concurrent treatments were not stated |
