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. 2019 Dec 23;23(2):117–124. doi: 10.1093/ijnp/pyz067

Figure 3.

Figure 3.

Sex differences in regulation of corticotropin-releasing factor (CRF) and CRFR1 mRNAs during early withdrawal from chronic cocaine administration. Fold changes (compared with male saline controls) in CRF (A–C) and CRFR1 (D) mRNAs are shown in the central amygdala (CeA; A) and bed nucleus of the stria terminalis (BNST; B–D) of male and female rats either 30 minutes (A, B, D) or 24 hours (C) following the last injection. ANOVA main effect of sex: ###P < .001, #### P < .0001. Post hoc tests: **P < .01, ***P < .001, ****P < .0001, n = 5–7 rats/group.