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. 2020 Mar 19;13:2347–2355. doi: 10.2147/OTT.S241818

Figure 5.

Figure 5

miR-136-5p could directly bind with CBX4.

Notes: (A) Binding site between CBX4 and miR-136-5p. (B) Effects of miR-136-5p overexpression on the expression of CBX4. Effects of FOXP4-AS1 (C) overexpression, and (D) knockdown on the expression of CBX4. (E) Relative luciferase activities in CC cells with luciferase activity vectors and synthesized miRNAs. (F) CBX4 was increased expression in CC cells. **P < 0.01, ***P < 0.001.

Abbreviations: FOXP4-AS1, forkhead box P4 antisense RNA 1; CBX4, chromobox 4; CC, cervical cancer; miR-136-5p, microRNA-136-5p; wt, wild-type; mt, mutant; NC-mimic, negative control miRNA for miR-136-5p mimic.