Figure 1.

Effect of BAE (50–1000 mg kg⁻¹ p.o.) and pregabalin (PGABA) (10–100 mg kg⁻¹ p.o.) on the vincristine-induced tactile allodynia in rats (von Frey 5 g). (a, b) The time-course effect; (c, d) the bar graphs of the AUCs. ^∗∗∗∗P < 0.0001; ^∗∗P < 0.01 compared with the vehicle-treated group (2-way RM ANOVA followed by Dunnett's post hoc test). ⁺⁺⁺⁺P < 0.0001; ⁺⁺P < 0.01 compared with the vehicle-treated group (ordinary 1-way ANOVA followed by Turkey's post hoc test). Each data presented are mean ± SEM (n = 10).