Table 3.
Baseline and follow-up HR-pQCT parameters of the distal tibia.
| Baseline | 24-week follow-up | Changes | p value | |
|---|---|---|---|---|
| Total vBMD (mg HA/cm3) | 200.2 ± 41.7 | 210.3 ± 40.9 | 10.01 ± 10.11 | 0.017 |
| Cortical area (mm2) | 89.9 ± 17.7 | 95.5 ± 19.9 | 5.60 ± 6.47 | 0.032 |
| Cortical vBMD (mg HA/cm3) | 870.3 ± 53.2 | 857.4 ± 60.0 | 8.60 (−78.60, 21.00) | 0.311 |
| Cortical perimeter (mm) | 114.0 ± 14.3 | 114.4 ± 14.2 | 0.33 ± 0.64 | 0.157 |
| Cortical thickness (mm) | 0.891 ± 0.197 | 0.944 ± 0.239 | 0.05 ± 0.07 | 0.028 |
| Intracortical porosity | 0.008 ± 0.003 | 0.010 ± 0.005 | 0.001 (−0.001, 0.009) | 0.094 |
| Trabecular area (mm2) | 795.3 ± 280.9 | 789.6 ± 211.4 | −5.71 ± 6.44 | 0.029 |
| Trabecular vBMD (mg HA/cm3) | 121.6 ± 29.4 | 128.0 ± 23.0 | 6.37 ± 10.20 | 0.098 |
| Trabecular thickness (mm) | 0.245 ± 0.034 | 0.248 ± 0.033 | 0.003 ± 0.011 | 0.482 |
| Trabecular number (1/mm) | 1.203 ± 0.318 | 1.253 ± 0.311 | 0.012 (−0.020, 0.219) | 0.102 |
| Trabecular separation (mm) | 0.878 ± 0.295 | 0.841 ± 0.269 | −0.004 (−0.250, 0.014) | 0.227 |
| Tb.1/N.SD (mm) | 0.396 (0.199, 0.964) | 0.389 (0.193, 0.995) | 0.001 (−0.108, 0.031) | 0.597 |
| Trabecular bone volume fraction | 0.193 ± 0.038 | 0.198 ± 0.036 | 0.004 ± 0.005 | 0.027 |
Data are presented as mean ± SD or median and ranges. vBMD, volumetric bone mineral density; Tb.1/N.SD, Std. dev. of 1/Tb.N, inhomogeneity of network.