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. 2020 Mar 10;21(5):1894. doi: 10.3390/ijms21051894

Figure 4.

Figure 4

Changes in the transcriptome of BY4741 yeast carrying different alleles of Med15 treated with MCHM and grown in YPD. (A) Differentially expressed mRNA from wildtype yeast (BY4741) compared to a med15 knockout strain grown in YPD. (B) Differentially expressed mRNA from wildtype yeast (BY4741) compared to a med15 knockout strain grown in YPD, then shifted to 400 ppm MCHM for 30 minutes displayed on a log scale. (C) Differentially expressed mRNA from wildtype yeast (BY4741) compared to a med15 knockout strain carrying Med15YJM789 expressed from a plasmid grown in YPD, then shifted to 550 ppm MCHM for 30 minutes. (D) Differentially expressed mRNA from wildtype yeast (BY4741) compared to a med15 knockout strain carrying Med15S288c expressed from a plasmid grown in YPD with G418, then shifted to 550 ppm MCHM for 30 min.