Skip to main content
. 2004 Dec 23;337(2):262–270. doi: 10.1016/j.ab.2004.10.003

Fig. 2.

Fig. 2

(A) Crystal structure of SARS CoV Mpro consists of two protomers A and B. Each protomer has three domains and the two protomers form a right angle at the domain III. The N finger of protomer B plugs into the domain II of protomer A. The green signs “<” represent the solvation water molecules. (B) The complex structure obtained by docking the octapeptide to SARS CoV Mpro and a follow-up energy minimization. The catalytic dyad of His-41 and Cys-145 is marked by an arrow and the peptide bond to be cleaved of the octapeptide is shown in green.