Table 1.
Demographic Data and Clinical Laboratory Indices of Patients Admitted to the Hospital With Suspected SARS*
Characteristics |
SARS Patients |
p Value |
|
---|---|---|---|
With Ribavirin Therapy (n = 44) | Without Ribavirin Therapy (n = 7) | ||
On hospital admission | |||
Age, yr | 36.4 ± 15.7 | 49.8 ± 26.1 | NS |
Gender | NS | ||
Male | 11 | 2 | |
Female | 33 | 5 | |
Underlying illnesses, No. | 9 (20%)† | 2 (29%)‡ | NS |
Initial Hb concentration, g/dL | 13.0 ± 1.5 | 13.1 ± 1.4 | NS |
Initial lymphocyte count, ×109 cells/L | 8.7 ± 5.3 | 8.5 ± 2.2 | NS |
Initial platelet count, ×103 cells/μL | 225.3 ± 149.9 | 206.3 ± 88.0 | NS |
Initial creatinine level, mg/dL | 1.0 ± 1.0 | 0.8 ± 0.1 | NS |
Initial AST level, IU/L | 37.1 ± 31.2 | 23.3 ± 7.4 | 0.018§ |
Initial ALT level, IU/L | 35.7 ± 39.2 | 13.6 ± 5.8 | NS |
Initial CPK level, IU/L | 190.4 ± 456.6 | 177.7 ± 219.4 | NS |
Initial LDH level, IU/L | 213.2 ± 86.4 | 137.0 ± 86.7 | 0.029§ |
During hospitalization | |||
Nadir Hb level, g/dL | 11.1 ± 1.8 | 12.0 ± 0.6 | NS |
Nadir absolute lymphocyte count, ×109 cells/L | 4.7 ± 2.1 | 5.1 ± 2.3 | NS |
Peak LDH level, IU/L | 392.8 ± 307.5 | 162.5 ± 98.0 | 0.017§ |
Peak CRP level, mg/dL | 10.3 ± 11.6 | 5.8 ± 6.2 | NS |
Values given as mean ± SD, unless otherwise indicated. AST = aspartate aminotransferase; ALT = alanine aminotransferase; CPK = creatinine phosphokinase; CRP = C-reactive protein; LDH = lactate dehydrogenase; Hb = hemoglobin; NS = not significant.
Included diabetes mellitus (four patients), seizures (one patient), rheumatoid arthritis (one patient), hepatitis B infection (one patient), congestive heart failure (one patient), and bacteremia (one patient).
Included two patients with hypertension.
p < 0.05 was considered to be significant.