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. 2015 Dec 24;128(1):263–272. doi: 10.1378/chest.128.1.263

Table 1.

Demographic Data and Clinical Laboratory Indices of Patients Admitted to the Hospital With Suspected SARS*

Characteristics
SARS Patients
p Value
With Ribavirin Therapy (n = 44) Without Ribavirin Therapy (n = 7)
On hospital admission
 Age, yr 36.4 ± 15.7 49.8 ± 26.1 NS
 Gender NS
  Male 11 2
  Female 33 5
 Underlying illnesses, No. 9 (20%) 2 (29%) NS
 Initial Hb concentration, g/dL 13.0 ± 1.5 13.1 ± 1.4 NS
 Initial lymphocyte count, ×109 cells/L 8.7 ± 5.3 8.5 ± 2.2 NS
 Initial platelet count, ×103 cells/μL 225.3 ± 149.9 206.3 ± 88.0 NS
 Initial creatinine level, mg/dL 1.0 ± 1.0 0.8 ± 0.1 NS
 Initial AST level, IU/L 37.1 ± 31.2 23.3 ± 7.4 0.018§
 Initial ALT level, IU/L 35.7 ± 39.2 13.6 ± 5.8 NS
 Initial CPK level, IU/L 190.4 ± 456.6 177.7 ± 219.4 NS
 Initial LDH level, IU/L 213.2 ± 86.4 137.0 ± 86.7 0.029§
During hospitalization
 Nadir Hb level, g/dL 11.1 ± 1.8 12.0 ± 0.6 NS
 Nadir absolute lymphocyte count, ×109 cells/L 4.7 ± 2.1 5.1 ± 2.3 NS
 Peak LDH level, IU/L 392.8 ± 307.5 162.5 ± 98.0 0.017§
 Peak CRP level, mg/dL 10.3 ± 11.6 5.8 ± 6.2 NS
*

Values given as mean ± SD, unless otherwise indicated. AST = aspartate aminotransferase; ALT = alanine aminotransferase; CPK = creatinine phosphokinase; CRP = C-reactive protein; LDH = lactate dehydrogenase; Hb = hemoglobin; NS = not significant.

Included diabetes mellitus (four patients), seizures (one patient), rheumatoid arthritis (one patient), hepatitis B infection (one patient), congestive heart failure (one patient), and bacteremia (one patient).

Included two patients with hypertension.

§

p < 0.05 was considered to be significant.