Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structure perturbation of K257/K258 double mutants. (a) Overlay of 15N-edited HSQC spectra from wild-type CTD (blue), K257R/K258R (green), and K257Q/K258Q (red) double mutants. Affected resonances are identified by their respective residue types and numbers in the wild-type protein. These are mapped onto the ribbon structure of the CTD dimer in (b).
