Supplementary Table 2.
Association Between Demographic Variables at Birth and Clinical Events in the First Year of Life (Infections, Gastrointestinal Illnesses, Failure to Thrive, and Hospital Readmission) and the Development of Crohn’s Disease, Under Age 10 Years Among All Persons With Crohn’s Disease Compared to Controls
| Effect | Comparison | OR estimate | 95% Wald confidence limits | P value |
|---|---|---|---|---|
| Infection year 1 | Yes vs no | 3.15 | 0.70, 14.14 | .13 |
| Socioeconomic status | ||||
| Q1 | Q2 vs Q1 | 2.21 | 0.79, 6.17 | .13 |
| Q2 | Q3 vs Q1 | 1.16 | 0.38, 3.54 | .79 |
| Q3 | Q4 vs Q1 | 1.64 | 0.53, 5.08 | .39 |
| Q4 | Q5 vs Q1 | 1.69 | 0.49, 5.83 | .40 |
| Geography | rural vs urban | 3.03 | 1.17, 7.84 | .02 |
| Apgar 1 min | 7+ vs <7 | 1.22 | 0.50, 2.97 | .66 |
| Gestational age | — | 0.91 | 0.75, 1.11 | .35 |
| Birth weight | — | 1.000 | 1.000, 1.001 | .46 |
| Readmitted in year 1 | No vs yes | 1.12 | 0.46, 2.75 | .80 |
| Cesarean section | Yes vs no | 0.48 | 0.19, 1.21 | .12 |
| Maternal IBD | Yes vs no | 9.22 | 1.80, 47.32 | .01 |
Q, quintile.