Table 3.
General comparison of the clinical characteristics of the critically ill with H1N1 in the three geographical H1N1 outbreak regions. *Pregnancy and obesity. **Percentage of general population obese
| Countries | Mexico31 | Canada50 | Australia/NZ74 |
|---|---|---|---|
| Scope | 6 hospitals | 38 adult/paediatric ICUs | All ICUs in Australia and NZ |
| Study design | Retrospective observational | Prospective observational | Inception cohort |
| No. of cases | 58 confirmed probable or suspected cases | 168 confirmed and probable cases | 722 confirmed cases |
| Rate of critical illness (% of those admitted to hospital) | 6.5% | 19% | No information |
| Co-morbidity* | 49% | 30.4% | 27.9% |
| Obesity | 36% (30%)** | 33.3% (24%)** | 28.6% (5.3%)** |
| Pregnancy | 1% | 13% | 9.1% |
| Invasive ventilation | 82% | 81% | 64.6% |
| Average days of ventilation | 12 | 12 | 8 |
| HFOV | 1.7% | 11.9% | No information |
| ECMO | 0 | 4.2% | 2.1% |
| Vasopressors | 58.6% | 32.7% | 35.3% |
| Renal support | No information | 7.1% | 5.3% |
| Mortality | 41.4% at 60 days | 14.3% at 28 days; 17.3% at 90 days | 14.3% at 99 days |