Table 2.
Revised Definition of Acute Exacerbation of IPF81
| Acute clinically significant respiratory deterioration characterized by evidence of new widespread alveolar abnormality |
| Diagnostic criteria |
| Previous or concurrent diagnosis of IPF |
| Acute worsening of dyspnea (within 1 mo) |
| CT evidence of diffuse infiltrates/ground glass/consolidation on a background of UIP pattern |
| Deterioration not fully explained by heart failure/fluid overload |
IPF = idiopathic pulmonary fibrosis; UIP = usual interstitial pneumonia.