Fig. 10.

Discovery of hepatitis C virus peptide entry inhibitors. The three protein fusion protein complex of HCV containing proteins E1, E2 and p7 was analyzed using WWIHS to identify putative membrane interacting sequences. The colored segments on the plot were peptides from a complete set of overlapping peptides that affected synthetic membranes (blue) or inhibited virus in vitro (red) [34]. The latter sequences are shown in the table.