Fig. 5.

Graphical representation of the bundle models of GT 1a (I), 1b (II) and 5a (III) from NMR at 0 ns (upper panel) and 100 ns (lower panel) (A). The structure shown for 5a is taken at 400 ns. The segments belonging to TMD1 and 2 are highlighted in green and red, respectively. The side chains of His-17 (bundle-1a, -1b, -5a) as well as His-31 and -59 of bundle-5a are highlighted. The view is from the side of the termini to the loop region. A side view of the respective structures is highlighting specific residues: His-17, -31, -59, Trp-30, Arg-35, -54, -57, -60 (B). Lipids and water molecules are omitted for clarity.