Table 5.
Mortality causes in the cohort studied
| Mortality after HSCT | No (%) |
|---|---|
| Total | 38 (22) |
| Causes | |
| Non-pulmonary etiologies | 26 (68) |
| Underlying disease progression | 9 (24) |
| GVHD | 8 (21) |
| Non-pulmonary infections | 3 (8) |
| Lymphoproliferative disorder | 3 (8) |
| Acute myocardical infarction | 1 (2) |
| Hemolytic anemia | 1 (2) |
| Trombotic microangiopathy | 1 (2) |
| Pulmonary etiologiesa | 12 (32) |
| Infectious | 9 (24) |
| P. aeruginosa | 3 |
| S. maltophila | 1 |
| E. faecium | 1 |
| P. aeruginosa+E. faecalis | 1 |
| P. aeruginosa+S. maltophila+RSV+ADV | 1 |
| CMV | 1 |
| Aspergillus | 1 |
| Non-infectious | 3 (8) |
| Non-specific intersticial pneumonia | 1 |
| Pulmonary drug toxicity | 2 |
Abbreviations: ADV=Adenovirus; HSCT=hematopoietic SCT; RSV=respiratory syncytial virus.
aPost-mortem examination was performed in 4 out of the 12 patients who died as a result of the pulmonary complication. In three cases, necropsy confirmed the clinical diagnosis of pneumonia; in one case, demonstrated an undiagnosed S. maltophila pneumonia and one last case demonstrated signs of diffuse pulmonary damage with negative cultures.