Table 1.

Clinical Features of Reported Human Avian Influenza Virus Infections and Outbreaks^*

Features	United States, 198012	United Kingdom, 199513	Hong Kong, 199715,16	Hong Kong, 199916	Hong Kong, 200317	The Netherlands, 200318	Southeast Asia, 2,003 to present19†	Canada, 200420
Animal source of human infection	Seal	Avian	Avian	Avian	Avian	Avian	Avian	Avian
Etiologic agent	A/H7N7	A/H7N7	A/H5N1	A/H9N2	A/H5N1	A/H7N7	H5N1	A/H7N3
Confirmed human cases, No.	3	1	18	2	2 (imported)	89	133	2
Fatalities, No. (case-fatality rate, %)	0 (0)	0 (0)	6 (33.3)	0 (0)	1 (50)	1 ( )	68 (51.1)	0 (0)
Presenting clinical syndromes	Conjunctivitis	Conjunctivitis	ILI, pneumonia	ILI	ILI, pneumonia	Conjunctivitis, ILI, pneumonia	ILI, pneumonia, diarrhea, encephalitis	Conjunctivitis, ILI

^*ILI = influenza-like illness.

^†Up to October 20, 2005.