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. Author manuscript; available in PMC: 2020 May 20.
Published in final edited form as: Nature. 2019 Nov 20;575(7784):699–703. doi: 10.1038/s41586-019-1763-5

Extended Data Figure 8 |. Circular plots for ecDNA.

Extended Data Figure 8 |

a-d, Composite circular plots displaying WGS, RNA-seq and ATAC-seq of ecDNA. For COLO320DM and PC3 cells with multiple versions of reconstructed structures, only one representative structure was shown. For TCGA samples (c, TCGA-A7-A0D9, breast invasive carcinoma; d, TCGA-L7-A6VZ, esophageal carcinoma), the ATAC-seq data point represents the highest signal within a 1 kb window.