Table 1.
Demographics and diagnostic criteria for the PML cohorts.
| Discovery (n = 70) | Replication (n = 115) | Total cases (n = 185) | ||||
|---|---|---|---|---|---|---|
| GENDER | ||||||
| Male | 44 | 74 | 118 | |||
| Female | 26 | 41 | 67 | |||
| ETHNICITY | ||||||
| EUR | 49 | 87 | 136 | |||
| AFR | 21 | 28 | 49 | |||
| PRIMARY DISEASE (EUR, AFR) | ||||||
| Blood cancer | 4 | (4, 0) | 18 | (18, 0) | 22 | (22, 0) |
| HIV | 53 | (32, 21) | 72 | (45, 27) | 125 | (77, 48) |
| MS | 9 | (9, 0) | 6 | (6, 0) | 15 | (15, 0) |
| Other | 4 | (4, 0) | 19 | (18, 1) | 23 | (22, 1) |
| PML DIAGNOSTIC CRITERIA | ||||||
| Compatible clinical features | 70 | 115 | 185 | |||
| Compatible imaging findings | 70 | 115 | 185 | |||
| CSF PCR for JCV is positive | 70 | 94 | 164 | |||
| Brain biopsy | 0 | 17 | 17 | |||