Skip to main content
. 2020 Mar 25;15(3):e0230647. doi: 10.1371/journal.pone.0230647

Fig 4. Spatial learning and memory and social behavior were not affected by the KO diet.

Fig 4

(A, B) Spatial learning and memory performance in the Barnes maze test. (A) The learning curve during trainings (Day 1–4, 3 trials per day). No significant differences were detected in latency to get the goal box (n = 8 per group). (B) Stay time in each quadrant area during the test session (Day 5). Both groups showed similar performance. (C-E) Social behavior in the three-chamber test. (C) Stay time in each chamber (n = 8 per group). Mice preferred to stay in a stranger chamber in both the control and KO diet groups. (D) Stay times in each chamber (n = 8 per group). Mice preferred to stay in a stranger chamber in both the control and KO diet groups. (E) Preference index, comparison of the time spent around the stranger mouse cage vs. empty cage and the stranger mouse cage vs. familiar mouse cage, which indicated that both groups of mice preferred novel stranger mice. All data are presented as mean and SEM. *: p < 0.05, ***: p < 0.001.