Table 4. Monoamine turnover rates in the NAc.
Male | ||||
Control | KO | p | ||
DOPAC / DA | 0.281 ± 0.057 | 0.175 ± 0.018 | 0.175 | |
3-MT / DA | 0.061 ± 0.008 | 0.042 ± 0.002 | 0.037 | * |
HVA / DA | 0.726 ± 0.229 | 0.260 ± 0.023 | 0.163 | |
5-HIAA / 5-HT | 0.403 ± 0.024 | 0.396 ± 0.029 | 0.711 | |
MHPG / NE | 0.313 ± 0.068 | 0.236 ± 0.012 | 0.654 | |
Female | ||||
Control | KO | p | ||
DOPAC / DA | 0.254 ± 0.023 | 0.169 ± 0.007 | 0.003 | * |
3-MT / DA | 0.074 ± 0.006 | 0.064 ± 0.003 | 0.361 | |
HVA / DA | 0.337 ± 0.056 | 0.201 ± 0.011 | 0.094 | |
5-HIAA / 5-HT | 0.599 ± 0.026 | 0.513 ± 0.014 | 0.021 | * |
MHPG / NE | 0.307 ± 0.018 | 0.341 ± 0.016 | 0.166 |
Mean ± SEM