Table 1.
The IDSA/ATS criteria remain the most pragmatic and robust tools to predict patients requiring ICU admission |
We recommend empirically covering PES pathogens in SCAP when at least two specific risk factors are present |
We recommend the use of prompt therapy with oseltamivir in patients with influenza CAP and avoidance of the use of steroids. Zanamivir can be used in cases of treatment failure and/or confirmed oseltamivir resistance |
We recommend a combination of a beta-lactam/beta-lactamase inhibitor or a third G cephalosporin plus a macrolide in most SCAP patients |
Patients with SCAP and septic shock should be managed with current practice guidelines. Corticosteroids can be used in cases of refractory shock and high systemic inflammatory response |
Based on available data, new antibiotics providing existing limitations in empiric therapy (including macrolide resistant species and MRSA) are needed |