Extended Data Table 4.

Experimental infection of SPF piglets using intestine tissue homogenate

Experimental details can be found in the Methods. a, Animals were recorded every day for signs of disease, including weight loss, diarrhoea and death. PCR on DNA from faecal swabs was carried out to monitor the presence of SADS-CoV or other pig viruses. b, Daily body weight record of all piglets. Weights are in kg.

*Euthanized on the indicated day for further analysis.

†Animal died during the experiment.

‡The only animal that did not receive colostrum in this experiment due to shortage in supply.