Table 1.
Patient characteristics and outcome parameters categorized by French Deprivation Index (FDep)
| Patient characteristics | All patients (n = 1834) | FDep nondeprived (n = 1228) | FDep deprived (n = 606) | p value* |
|---|---|---|---|---|
| FDep | − 0.6 [− 1.6; 0.3] | − 1.1 [− 2.1; − 0.6] | 0.7 [0.3; 1.1] | < 0.001 |
| Epidemiological data | ||||
| Age (years) | 63 [50; 74] | 63 [51; 75] | 62 [49; 72] | 0.024 |
| Male gender (%) | 1190 (64.9%) | 794 (64.7%) | 396 (65.3%) | 0.771 |
| Body mass index (kg/m2) | 26.4 [23.1; 30.7] | 26.1 [23; 30.5] | 27.2 [23.5; 31.1] | 0.016 |
| Past medical history, no. (%) | ||||
| Charlson score | 3 [1, 5] | 3 [1, 5] | 3 [1, 5] | 0.431 |
| Alcohol abuse | 319 (17.4%) | 214 (17.4%) | 105 (17.4%) | 0.976 |
| Depression | 233 (12.7%) | 165 (13.4%) | 68 (11.3%) | 0.186 |
| HIV | 46 (2.5%) | 36 (2.9%) | 10 (1.7%) | 0.100 |
| Loss of autonomy | 70 (3.8%) | 52 (4.2%) | 18 (3%) | 0.187 |
| Other psychiatric disorder | 80 (4.4%) | 61 (5%) | 19 (3.1%) | 0.072 |
| Cognitive dysfunction | 31 (1.7%) | 22 (1.8%) | 9 (1.5%) | 0.637 |
| COPD | 240 (13.1%) | 147 (12%) | 93 (15.4%) | 0.042 |
| Active malignant tumor | 246 (13.4%) | 157 (12.8%) | 89 (14.7%) | 0.253 |
| Chronic liver disease | 140 (7.6%) | 90 (7.3%) | 50 (8.3%) | 0.475 |
| Prior stroke | 69 (3.8%) | 55 (4.5%) | 14 (2.3%) | 0.022 |
| Prior myocardial infarction | 68 (3.7%) | 47 (3.8%) | 21 (3.5%) | 0.707 |
| Smoking | 489 (26.7%) | 335 (27.3%) | 154 (25.5%) | 0.412 |
| ICU admission diagnosis, no. (%) | 0.006 | |||
| Septic shock | 419 (22.9%) | 269 (21.9%) | 150 (24.8%) | |
| Acute respiratory failure | 352 (19.2%) | 232 (18.9%) | 120 (19.8%) | |
| Acute neurological disorder | 256 (14%) | 184 (15%) | 72 (11.9%) | |
| Out-of-hospital cardiac arrest | 161 (8.8%) | 125 (10.2%) | 36 (5.9%) | |
| Trauma | 86 (4.7%) | 50 (4.1%) | 36 (5.9%) | |
| Organ dysfunction scores | ||||
| SAPS II score at admission | 48 [35; 62] | 49 [36; 63] | 46 [35; 61] | 0.084 |
| SOFA score at admission | 7 [5, 10] | 8 [5, 10] | 7 [5, 11] | 0.974 |
| Status at admission | ||||
| SBP | 122 [109; 139] | 122 [109; 139] | 123 [108; 140] | 0.854 |
| DBP | 60 [53; 70] | 61 [53; 70] | 60 [53; 70] | 0.826 |
| HR | 90 [77; 105] | 90 [77; 105] | 90 [78; 105] | 0.921 |
| Creatinine | 82.8 [58.8; 147] | 85 [60; 156] | 79 [57; 134] | 0.030 |
| eGFR | 78.5 [40.9; 119.4] | 76.3 [38.1; 116.6] | 84.5 [45.9; 126.8] | 0.023 |
| Lactate | 1.4 [1; 1.9] | 1.4 [1; 1.9] | 1.5 [1.1; 2.1] | 0.01 |
| WBC count (g/l) | 10.8 [7.5; 16.0] | 10.9 [7.7; 16.0] | 10.7 [7.3; 16.3] | 0.909 |
| Hemoglobin | 9.9 [8.9; 11.4] | 9.9 [8.9; 11.4] | 10 [8.9; 11.5] | 0.991 |
| Platelet count (g/l) | 166 [101; 247] | 167 [102; 248] | 159 [95.0; 244] | 0.237 |
| Organ support/in ICU management | ||||
| Mechanical ventilation | 1714 (93.5%) | 1149 (93.6%) | 565 (93.2%) | 0.787 |
| Tracheotomy | 284 (15.5%) | 182 (14.8%) | 102 (16.8%) | 0.263 |
| FFP transfusion (%) | 326 (17.8%) | 180 (14.7%) | 146 (24.1%) | < 0.001 |
| Inotrope/vasopressor (%) | 1405 (76.6%) | 931 (75.8%) | 474 (78.2%) | 0.253 |
| RBC transfusion (%) | 848 (46.2%) | 535 (43.6%) | 313 (51.7%) | 0.001 |
| RRT (%) | 435 (23.7%) | 289 (23.5%) | 146 (24.1%) | 0.792 |
| Vasopressor (%) | 120 (6.5%) | 79 (6.4%) | 41 (6.8%) | 0.787 |
| Status at discharge | ||||
| SBP | 123 [109; 138] | 122 [108; 138] | 124 [110; 140] | 0.247 |
| DBP | 67 [57; 76] | 67 [57; 75] | 66 [56; 77] | 0.994 |
| HR | 89 [78; 101] | 90 [78; 101] | 89 [78; 100.8] | 0.793 |
| Creatinine | 68 [52; 103.2] | 69 [52.4; 105] | 67 [51; 100] | 0.151 |
| eGFR | 99.2 [60.2; 139.4] | 98.1 [58.6; 137.5] | 102.3 [62.6; 142] | 0.087 |
| Lactate | 1.4 [1; 2.1] | 1.4 [1; 2.1] | 1.4 [1; 2.1] | 0.581 |
| WBC count (g/l) | 9.8 [7.2; 13.9] | 9.7 [7.2; 13.7] | 10 [7.1; 14.0] | 0.387 |
| Hemoglobin | 9.9 [8.8; 11.1] | 9.9 [8.8; 11.1] | 9.8 [8.8; 11] | 0.813 |
| Platelet count (g/l) | 275 [169; 425] | 280 [169; 428] | 270 [170; 422] | 0.618 |
| Outcome parameters | ||||
| ICU LOS (days) | 13 [7, 22] | 12 [7, 21] | 14 [8, 22] | 0.097 |
| Hospital LOS (days) | 23 [12; 40] | 23 [12; 40] | 24 [13; 40] | 0.19 |
| ICU mortality (%) | 387 (21.1%) | 256 (20.8%) | 131 (21.6%) | 0.704 |
| In-hospital mortality (%) | 490 (26.7%) | 320 (26.1%) | 170 (28.1%) | 0.364 |
| 28-day mortality (%)a | 117 (8.1%) | 72 (7.4%) | 45 (9.5%) | 0.172 |
| 1-year mortality (%)a | 274 (19%) | 177 (18.2%) | 97 (20.5%) | 0.304 |
COPD chronic obstructive pulmonary disease, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, FDep French Deprivation Index, FFP fresh frozen plasma, HIV human immunodeficiency virus, HR heart rate, ICU intensive care unit, LOS length of stay, RBC red blood cell, RRT renal replacement therapy, SAPS Simplified Acute Physiology Score, SBP systolic blood pressure, SOFA Sepsis-related Organ Failure Assessment, WBC white blood cell
*p value from Chi-squared test or Mann–Whitney test
aAmong ICU survivors