Table 1.
Characteristics of the 41 H5N1-infected patients reported in the medical literature who required advanced life support. Due to variability in reporting the sample size varies for different characteristics. Confidence intervals are not given for the proportion of patients with organ failures, ARDS or pneumothorax. These data represent only rough estimates as organ failures were poorly defined in most reports (IQR interquartile range, CI 95% confidence interval)
| Characteristic | n | Summary data |
|---|---|---|
| Age, median (years) | 41 | 13 (IQR 6–24) |
| Sex: M:F | 41 | 21:20 |
| Hospital mortality | 41 | 90% (CI 81–99%) |
| Duration of symptoms prior to hospital admission, median (days) | 30 | 5 (IQR 4–6) |
| Duration of hospital stay prior to requirement for advanced organ support, median (days) | 16 | 2 (IQR 0.75–3.25) |
| Time from hospital admission to death, median (days) | 21 | 6 (IQR 5–13) |
| Proportion with organ failures | 41 | |
| Multiorgan failure | 68% | |
| Respiratory failure | 98% | |
| Cardiovascular failure | 44% | |
| Haematological | 29% | |
| Central nervous system | 2% | |
| Renal | 24% | |
| Hepatic | 7% | |
| Gastrointestinal | 41% | |
| Proportion with ARDS | 41 | 54% |
| Proportion with pneumothorax | 41 | 17% |