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. 2020 Mar 18;14:161. doi: 10.3389/fnins.2020.00161

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Copyright © 2020 Chang, Ardiles, Tapia-Rojas, Araya, Inestrosa, Palacios and Acosta.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Iba-1 immunolabelling of degus central retina. (A’) Young, 18-month old degus, (B’) Adult, 48-month old degus, (C’) Aged adult, 84-month old degus. Representative images of increased activation of microglia as a function of age. (D) Quantification of number of Iba-1 per unit area was conducted in n = 4 retina per age group. Young retinas had inactive microglial cells (A), while they were dendritic-like in adult retina. (B). The aged adult group did not seem to have active microglia (C). Statistical analysis was completed by one way ANOVA. Significant values are indicated with asterisks: *p < 0.05. Scale bar = 40 μm.