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. 2005;437(7059):764–769. doi: 10.1038/nature03956

Figure 2. The E16 binding site defines a West Nile virus dominant neutralizing epitope that is divergent in other flaviviruses.

Figure 2

a, Sequence of the four segments of West Nile virus (WNV) DIII contacted by E16 aligned with the analogous residues of other flaviviruses. The DIII residues contacted by E16 are highlighted in blue and magenta, and deletions are indicated with a hash symbol. DEN, dengue virus; JEV, Japanese encephalitis virus; TBEV, tick-borne encephalitis virus; YFV, yellow fever virus. b, Structure of the West Nile virus dominant neutralizing epitope as defined by the E16–DIII complex.