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. 2005 Jan 23;11(2):160–166. doi: 10.1038/nm1179

Figure 1. ACE acts as a GPI anchored protein–releasing factor.

Figure 1

(a) A single 100-kDa band isolated by the TSK gel 3000SW column was subjected to SDS-PAGE and silver stained. (b) Immunoblotting of released PLAP from reaction with purified ACE-t, ACE-S, PI-PLC or vehicle alone (Buffer). 'Input' indicates substrate of the reaction. The size of the products released by ACE and PI-PLC was similar to that of the substrate. (c) Dose dependence of ACE-S GPIase activity. The results of experiments in which captopril was applied are also indicated. Values are mean ± s.d., n = 3.