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. 2004 Feb 22;10(3):290–293. doi: 10.1038/nm1001

Figure 2. Antiviral activity of pegylated IFN-α against SCV in vitro and its biological activity in macaques.

Figure 2

(a) Effect of pegylated IFN-α against SCV infection in vitro. Similar results were obtained in three separate experiments. (b) Pharmacokinetic analysis of pegylated IFN-α (b) and induction of neopterin (c) in macaques treated with PBS (□, control group; n = 4) or pegylated IFN-α (▪, prophylactic group; n = 4) on days −3 and −1. Data are expressed as mean ± s.d. **, P < 0.01 compared with control.