TABLE II.
Treatment and survival by inpatient or outpatient status at the time of brain metastasis diagnosis
| Variable | Age group | p Value | |
|---|---|---|---|
| <40 Years | ≥ 40 Years | ||
| Patients (n) | 17 | 104 | 0.059a |
|
| |||
| Outpatient or inpatient statusb | |||
| Outpatient [n (%)] | 13 (76) | 54 (52) | |
| Mean survival (months) | 24 | 7 | 0.001c |
| Inpatient [n (%)] | 4 (24) | 50 (48) | |
| Mean survival (months) | 13 | 8 | 0.248c |
|
| |||
| Local treatment status [n (%)] | 17 | 104 | <0.001 |
| Supportive care | 0 (0) | 14 (13.5) | |
| No local treatment; any systemic treatment | 2 (12) | 12 (11.5) | |
| Brain surgery ± RT | 1 (6) | 13 (12.5) | |
| Brain RT, no brain surgery | 14 (82) | 65 (62.5) | |
|
| |||
| Systemic treatment status [n (%)] | 17 | 104 | <0.001 |
| CTx, anti-HER2 therapyd, ± hormonal therapy | 12 (71) | 37 (36) | |
| Hormonal therapy (without CTx) | 2 (12) | 16 (15) | |
| None | 3 (18) | 51 (49) | |
|
| |||
| Cohort receiving systemic treatment (n) | 14 | 53 | 0.014 |
| Mean survival (months) | 21 | 6 | |
| 1-Year survival (%) | 63 | 26 | |
| 2-Year survival (%) | 42 | 10 | |
a
Relationship between inpatient or outpatient status and age.
b
At the time of brain metastasis diagnosis.
c
Relationship between mean survival in months and age.
d
When appropriate.
RT = radiation therapy; CTx = chemotherapy.