Table VI.
Characteristics of infants missing baseline creatinine excluded from the study vs final study population
| Characteristics | Missing baseline creatinine (n = 318) | Study population (n = 1017) | P value* |
|---|---|---|---|
| Age (days) at start of acyclovir | 9 (4–20) | 6 (2–18) | .03 |
| Weight (g) at start of acyclovir | 3400 (2860–3890)† | 3180 (2700–3700) | <.01 |
| Preterm gestation (<37 wk) | 59 (27.1)‡ | 274 (26.9) | .92 |
| Hospital | <.01 | ||
| 1 | 23 (7.2) | 182 (17.9) | |
| 2 | 167 (52.5) | 330 (32.5) | |
| 3 | 4 (1.3) | 43 (4.2) | |
| 4 | 124 (39.0) | 462 (45.4) | |
| Tested for HSV | 260 (81.8) | 942 (92.6) | <.01 |
| HSV+ PCR | 13 (4.1) | 31 (3.0) | .48 |
| Days of acyclovir administration | 2 (2–4) | 2 (2–3) | .65 |
| Location of first acyclovir dose | <.01 | ||
| Floor/other | 139 (44.1)§ | 239 (23.5) | |
| PICU | 32 (10.2) | 184 (18.1) | |
| NICU | 144 (45.7) | 594 (58.4) |
PCR, polymerase chain reaction.
Values are number (%) or median (IQR).
*
The χ2 tests or Fisher exact tests (if cells <5) were used to compare proportions of categorical or binary variables. Wilcoxon rank-sum tests were used to compare distribution of continuous covariates.
†
Data available for 316 of 318 infants with missing baseline.
‡
Data available for 218 of 318 infants with missing baseline.
§
Data available for 315 of 318 infants with missing baseline.