Table V.

Decrease in incidence rates of major amputations associated with multidisciplinary teams for patients with diabetic foot ulcers

Study, Country	Bias score (1)	Incidence of major amputation /100,000 inhabitants with diabetes Controls	Incidence of major amputation/100,000 inhabitants with diabetes Multidisciplinary Teams	Decrease in incidence with multidisciplinary teams
Williams 2018, United Kingdom	16	412*	44*	368*
Jiménez 2017, Spain	15.5	6.1**	4.5**	1.6**
Witsø 2010, Norway	14.5	400***	240***	160***
Anichini 2007, Italy	14	6.3	3.1	3.2
Holstein 2000, Denmark	13.5	27.2	6.9	20.3
Troisi 2016, Italy	11.5	37.5	28.7	8.8

⁽¹⁾Studies are ordered based on bias scores, with higher quality studies listed first.

^*Williams and colleagues expressed the incidence of major amputation based on 100,000 inhabitants with diabetes, adjusted for age and sex.

^**Jiménez and colleagues expressed the incidence of major amputation based on 100,000 general inhabitants per year.

^***Witsø and colleagues expressed the incidence of major amputation based on 100,000 inhabitants with diabetes per year.