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Percent reduction in Nav1.1 and Nav1.6 peak INa from control following the perfusion of 10, 100 or 500 nM 4,9-ah-TTX. Values represent the mean ± S.E.
| Reduction in Peak INa Following Perfusion of 4,9-ah-TTX | ||||
|---|---|---|---|---|
| [4,9-ah-TTX] | (% of Control) | |||
| Nav 1.1 | N | Nav 1.6 | N | |
| 10nM | 11 % (± 4) | 4 | 18 % ( ±2) | 4 |
| 100nM | 46 % ( ± 5) | 5 | 39 % ( ±2) | 4 |
| 500 nM | 64 % ( ± 4) | 5 | 76 % ( ±2) | 3 |
