. 2020 Feb 10;6(1):18–26. doi: 10.1016/j.cdtm.2019.12.008

Table 1.

Characteristics of randomized controlled trials included in the meta-analysis.

References	Province	ACEI/ARBs	ACEI/ARBs + TG	Trial duration	Sample size	Study design	Primary outcome	Dropout
Chen 2012¹⁹	Xizang	Erbesartan 150 mg qd	Erbesartan 150 mg qd; TG 40 mg qd	3 months	50	Random number table	24-h UTP SCr	0
Song 2005²⁰	Shandong	Benazepril 5–20 mg qd	Benazepril 5–20 mg qd; TG 1–2 mg/kg qd	6 months	67	Lottery	24-h UTP SCr	0
He 2016²¹	Guizhou	Benazepril 5 mg bid	Benazepril 5 mg bid; TG 0.3–0.5 mg/kg bid/tid	2 months	70	Random number table	24-h UTP	0
Zhang 2012²²	Guangzhou	Erbesartan 75 mg bid	Erbesartan 75 mg bid; TG 10–20 mg tid	6 months	100	Envelope method	24-h UTP SCr	0
Tu 2017²³	Zhejiang	Telmisartan 40 mg qd	Telmisartan 40 mg qd; TG 1.5 mg/kg tid	1 months	216	Random number table	24-h UTP SCr	0
Wu 2018²⁴	Zhejiang	Valsartan 80–160 mg qd	Valsartan 40–80 mg qd; TG 10–20 mg tid	6 months	68	Random number table	24-h UTP SCr	0
Zhang 2016²⁵	Hebei	Valsartan 80 mg qd	Valsartan 80 mg qd; TG 30 mg bid	12 months	140	Random number table	24-h UTP SCr	9^a
Li 2015²⁶	Beijing	Erbesartan 150 mg qd	Erbesartan 150 mg qd; TG 40 mg qd	6 months	60	Random number table	24-h UTP SCr	3^b
Song 2014²⁷	Henan	Valsartan 40–80 mg qd	Valsartan 40–80 mg qd; TG 20 mg tid	6 months	80	Random number table	24-h UTP SCr	0

TG: Tripterygium glycoside; ACEI: angiotensin-converting enzyme inhibitor; ARBs: angiotensin receptor blockers; ACEI/ARBs: angiotensin-converting enzyme inhibitors/angiotensin receptor blockers; tid: 3 times daily; bid: 2 times daily; qd: once a day; 24-h UTP: 24-h urine total protein quantitation; SCr: serum creatinine.

In the ACEI/ARBs + TG group, four patients dropped out. Two were excluded because they were not strictly prescribed according to the doctor's orders and two were rejected because of missing visits; in the ACEI/ARBs group, five patients dropped out. One was excluded because they were not strictly prescribed according to the doctor's orders, one was rejected because of missing visits and three dropped out without reason.

Two patients dropped out in the ACEI/ARB group because of repeated hyperkalemia; one patient dropped out in the ACEI/ARBs + TG group because of increased alanine aminotransferase.