Table 2.
Sensitivity analyses | k | N | Hedges' g | 95% CI | p-value | Heterogeneity |
---|---|---|---|---|---|---|
Primary meta-analysis | 12 | 431 | −0.47 | −0.71 to −0.24 | p < 0.0001 | Q = 15.06, df = 11, p = 0.18, T2 = 0.0313, I2 = 27% |
• Random allocation: low-risk of bias | 10 | 379 | −0.46 | −0.74 to −0.17 | p = 0.0018 | Q = 14.9, df = 9, p = 0.09, T2 = 0.0754, I2 = 39.6% |
• Concealed allocation: low-risk of biasa | 2 | 105 | −0.10 | −0.49 to −0.28 | – | – |
• Blinding of assessors: low-risk of biasb | 1 | 26 | −0.62 | −0.1.41 to 0.17 | – | – |
• Completeness of follow-up: low-risk of bias | 6 | 237 | −0.50 | −0.83 to −0.18 | p = 0.0022 | Q = 8.28, df = 5, p = 0.14, T2 = 0.0293, I2= 39.6% |
• Intention-to treat analysis: low risk of bias | 5 | 257 | −0.45 | −0.77 to −0.13 | p = 0.0063 | Q = 7.7, df = 4, p = 0.1, T2 = 0.0347, I2 = 48.1% |
• Only peer-reviewed articles | 7 | 308 | −0.56 | −0.90 to −0.23 | p = 0.0011 | Q = 11.48, df = 6, p = 0.07, T2 = 0.0839, I2 = 47.7% |
k number of effect size estimates, N number of participants, Hedges' g pooled effect size estimate, CI confidence interval.
The two included studies rated low-risk of bias for “concealed allocation” are Carter et al. (2015) and Jeong et al. (2005).
The only included study rated low-risk of bias for “blinding of assessors” is Hughes et al. (2013).