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. 2020 Mar 19;10:353. doi: 10.3389/fonc.2020.00353

Table 1.

Baseline characteristics of patients.

Characteristic HCC MVI (-) (n = 178) HCC MVI (+)
(n = 144)
P-value
Age (year) 0.304
    Mean ± SD 58 ± 11 57 ± 9
    Range 20–81 29–74
Male/female 143/35 129/15 0.037
Etiology of liver disease
    Hepatitis B 137 120
    Hepatitis C 3 5
    Alcohol 1 0
    NAFLD 12 5
    Absence 25 14
AFP (ng/l) 28 ± 10 506 ± 8 <.001*
CA 19-9 38 ± 7 425 ± 19 0.784
CEA 4.8 ± 1.3 9.7 ± 5.5 0.635
Tumor size (mm) <0.001*
    Mean ± SD 32.3 ± 23.3 48.4 ± 30.6
    Range 9–144 6–176

HCC, hepatocellular carcinoma; MVI, microvascular invasion; AFP, Alpha-fetoprotein; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; NAFLD, non-alcoholic fatty liver disease.