Table 1.

Action potential parameters recorded simultaneously in the left atria and the pulmonary veins in basal conditions and at the steady-state of the cirazoline 10⁻⁶ M superfusion.

	DMP (mV)	AP peak (mV)	APA (mV)	P0 dV/dtmax (V/s)	APD90 (ms)
LA basal	−74.4 ± 0.6	18.4 ± 1.0	92.8 ± 1.2	172 ± 10	36.3 ± 1.8
LA cirazoline	−71.6 ± 0.7	14.5 ± 1.0	86.1 ± 1.1	144 ± 12	44.7 ± 2.5*
PV basal	−73.9 ± 0.9	17.6 ± 1.8	91.1 ± 2.2	192 ± 11	46.5 ± 2.6
PV cirazoline	−45.1 ± 2.1***	−39.5 ± 2.0	5.4 ± 1.6***	—	—

DMP (diastolic membrane potential), AP peak (maximum voltage of action potential), APA (action potential amplitude), P0 dV/dtmax (phase 0 maximum rate of depolarization) and APD90 (action potential duration at 90% of repolarization). Mean ± SEM of results obtained from 14 different preparations electrically paced at 5 Hz in the LA. *P < 0.05 and ***p < 0.001 vs basal condition.