Figure 3.

Results of 5-fold cross validated linear discriminant model: (a) Output of classifier as projected on complete surgical resection. Only collagen pixels were classified as either ECM3 or non-ECM3. Bottom row shows zoom-in sections from samples marked by red boxes. (b) Receiver operating characteristic curve for classifier output. ECM3 positive label was selected as positive class label. Posterior probability of classification was used for calculating false positive rate and true positive rate. Optimal operating point (Opt) was identified using the procedure described in methods.