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SAL treatment prevented the onset of diabetes in ZDF rats. (A) Serial changes in food intake. (B) Serial changes in body weight. (C–E) OGTT for rats age 6 weeks (C), 9 weeks (D), and 12 weeks (E). (F) AUCg determined by OGTT. One-way ANOVA followed by Tukey's test compared differences between group pairs. Data are means ± SEM. *P < 0.05 vs. ZL rats; #P < 0.05 vs. ZDF rats. (G, H) Ratios of IGT and diabetes in rats age 9 weeks (G) and 12 weeks (H).
