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. 2020 Mar 19;11:300. doi: 10.3389/fphar.2020.00300

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Copyright © 2020 Zhang, Cui, Jin, Han, Wang, Yang, Xu, Shan, Gao, Li, Zuo, Yang and Chang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SAL improved islet-cell function and insulin resistance in ZDF rats. (A) Effects of SAL on lipid metabolism in rats age 12 weeks. Fasting plasma glucagon (B) and (C) HOMA-IR values in rats. (D, E) Insulin concentrations (D) and HOMA-β values (E) in rats. One-way ANOVA followed by Tukey's test compared differences between group pairs. Data are means ± SEM. *P < 0.05 vs. ZL rats; ^#P < 0.05 vs. ZDF rats.