Figure 2.

Effect of beta-lactam antibiotics on ROS production and cell migration of scratched cells. Mean relative fluorescence (A,C) and mean wound area (B,D) measured over 36 h of scratched fibroblasts (A,B) and HNECs (C,D) treated with the beta-lactam antibiotics amoxicillin (blue line) or augmentin (black line) or scratched untreated control (green line and green shaded area). Y-values in (A,C) represent mean percentage of additional fluorescence emitted by scratched monolayers above unscratched, untreated controls ± SEM error bars (n = 3). Y-values in (B,D) represent mean proportion of original wound area remaining ± SEM error bars (n = 3).