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. 2020 Mar 19;7:31. doi: 10.3389/fcvm.2020.00031

Table 2.

Impact of Additive solution treatment on the microRNA profile of platelet-derived MPs.

Top 20 Fold change Upregulated Fold change Downregulated Fold change
hsa-miR-146a-5p 0.7 hsa-let-7f-5p 2.4 hsa-miR-151a-3p 0.4
hsa-miR-151a-3p 0.4 hsa-miR-1-3p 2.3 hsa-miR-320a 0.3
hsa-miR-126-3p 1.3 hsa-miR-101-3p 2.1 hsa-miR-221-3p 0.4
hsa-miR-320a 0.3 hsa-miR-107 2.3 hsa-miR-186-5p 0.3
hsa-miR-221-3p 0.4 hsa-miR-142-3p 2.2 hsa-miR-423-5p 0.5
hsa-miR-21-5p 1.5 hsa-miR-143-3p 2.1 hsa-miR-1307-3p 0.4
hsa-miR-30d-5p 0.7 hsa-miR-144-3p 2.7 hsa-miR-320c 0.3
hsa-miR-148a-3p 1.5 hsa-miR-145-5p 3.3 hsa-miR-486-5p 0.5
hsa-let-7i-5p 1.1 hsa-miR-150-5p 2.5 hsa-miR-4433b-3p 0.4
hsa-miR-26a-5p 2.8 hsa-miR-182-5p 2.0 hsa-miR-320b 0.3
hsa-miR-423-3p 0.6 hsa-miR-199b-5p 2.3 hsa-miR-361-3p 0.5
hsa-miR-191-5p 1.1 hsa-miR-23a-3p 2.2 hsa-miR-185-3p 0.2
hsa-miR-22-3p 0.8 hsa-miR-23b-3p 3.7 hsa-miR-326 0.3
hsa-miR-186-5p 0.3 hsa-miR-26a-5p 2.8 hsa-miR-425-3p 0.4
hsa-miR-140-3p 0.7 hsa-miR-26b-5p 2.8 hsa-miR-532-5p 0.4
hsa-miR-423-5p 0.5 hsa-miR-32-5p 2.2 hsa-let-7d-3p 0.5
hsa-miR-185-5p 1.3 hsa-miR-335-3p 2.0 hsa-miR-629-5p 0.5
hsa-let-7g-5p 1.8 hsa-miR-340-3p 2.1 hsa-miR-576-3p 0.4
hsa-miR-451a 1.8 hsa-miR-3613-5p 2.8 hsa-miR-345-5p 0.4
hsa-miR-1307-3p 0.4 hsa-miR-369-3p 3.1 hsa-miR-6852-5p 0.3
hsa-miR-379-5p 2.4 hsa-miR-1260b 0.4
hsa-miR-410-3p 2.2 hsa-miR-769-5p 0.3
hsa-miR-411-5p 3.0 hsa-miR-320c 0.3
hsa-miR-487b-3p 2.4 hsa-miR-99b-3p 0.4
hsa-miR-494-3p 2.0 hsa-miR-139-3p 0.1
hsa-miR-2355-3p 0.3
hsa-miR-6842-3p 0.4
hsa-miR-760 0.3
hsa-miR-501-3p 0.3
hsa-miR-1908-5p 0.2
hsa-miR-215-5p 0.4
hsa-miR-2110 0.3
hsa-miR-338-5p 0.4
hsa-miR-574-3p 0.5
hsa-miR-92b-3p 0.5
hsa-miR-1250-5p 0.2
hsa-miR-320d 0.2
hsa-miR-320d 0.2
hsa-miR-29c-5p 0.3

The 20 most abundant microRNAs are displayed, along with the microRNAs that were the most impacted (downregulated or upregulated) by Additive solution treatment.

Data are expressed as fold change vs. MPs derived from control platelets.