Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 19;11:306. doi: 10.3389/fphar.2020.00306

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Cao, Tian, Li, Lv, Han, Zhuang, Cheng, Gong, Ying, Jin and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

EPO downregulated the expression and concentration of IL-1β and IL-18 in LPS-induced ALI. EPO (5 U/g) was injected into the peritoneal cavity of mice after LPS (15 mg/kg) stimulation. The mice were sacrificed 8 h later, and the serum was obtained to measure the concentrations of IL-1β and IL-18 (A,D) by ELISA. The lung tissues were harvested to measure the concentrations of IL-1β and IL-18 (B,E) by ELISA, and the mRNA expression levels of pro-IL-1β and pro-IL-18 (C,F) were measured by QPCR. The data are presented as the mean ± SD. The differences among groups were assessed by one-way ANOVA and the post hoc test (Turkey method) was applied to investigate the differences one by one. n = 8 per group.