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Most attenuated measles vaccines were developed from the Edmonston strain of measles virus. The Edmonston B vaccine was the first licensed measles vaccine but was associated with a high frequency of fever and rash. The further attenuated Schwarz and Edmonston-Zagreb vaccines are widely used throughout the world, although the Moraten vaccine is the only measles vaccine used in the United States. Modified with permission from Ref. 88 (1993) WHO.
