Table 2.

Effect of Met and GAA supplementation on plasma concentrations of GAA, creatine, and creatinine on days 3 and 6

Plasma, mg/L	Day		GAA, g/d						P-value1
		Met, g/d	0	10	20	30	40	SEM	Day	Met	GAA	M × G	M × D	G × D	M × G × D
GAA	3	0	1.08	0.96	1.57	1.57	2.22	0.25	0.02	0.35	<0.0001	0.32	0.07	0.91	0.05
		12	0.67	1.06	1.19	2.23	2.14
	6	0	0.98	1.36	2.08	2.63	2.59
		12	1.19	1.26	1.37	1.85	1.94
Creatine	3	0	27.1	30.1	32.8	37.8	35.7	2.1	<0.0001	0.51	<0.0001	0.64	0.10	0.08	0.01
		12	26.4	31.0	30.2	33.6	29.1
	6	0	26.0	31.0	30.9	31.5	25.9
		12	26.4	28.4	28.0	30.0	29.7
Creatinine	3	0	9.36	9.73	11.60	10.97	10.96	0.39	<0.01	0.11	<0.0001	0.09	0.32	0.34	0.29
		12	8.49	9.85	9.74	9.89	9.88
	6	0	9.04	9.57	10.19	9.80	9.99
		12	8.51	8.78	9.23	9.14	9.59

¹M × G = Met × GAA; M × D = Met × day; G × D = GAA × day; M × G × D = Met × GAA × day.