Table 3.
A descriptive summary of GWAS for 15 body size traits (Pwald < 5 × 10–8)
| Associated loci | Leading variants | MAF | −Log10Pwald | Traits | Nearest gene |
|---|---|---|---|---|---|
| 2:74232049-76428806 | 2:76123001 | 0.293 | 8.27 | HCH | CNTNAP5 |
| 2:77234797-79549419 | 2:77705883 | 0.259 | 7.36 | HCH | CNTNAP5 |
| 3:48619698-49685573 | 3:48903215 | 0.454 | 7.59 | CAC | F3 |
| 4:61097399-61109497 | 4:61097399 | 0.194 | 7.48 | HCH | EEPD1 |
| 4:90719918-91208754 | 4:91135749 | 0.068 | 7.61 | CC | GRM8 |
| 5:49425124-49524195 | 5:49522901 | 0.105 | 9.06 | CC | C5H12orf66 |
| 5:108168319-108851195 | 5:108451308 | 0.404 | 7.44 | BL | CACNA1C |
| 6:25768970-31681813 | 6:26182890 | 0.136 | 8.68 | FS | RAP1GDS1 |
| 6:30080542-30099052 | 6:30087434 | 0.090 | 7.94 | CD | PDLIM5 |
| 6:38272742-38308265 | 6:38272802 | 0.148 | 8.18 | IW | LCORL |
| 6:60373051-60432904 | 6:60391823 | 0.080 | 7.46 | FS | LIMCH1 |
| 7:68161294-68306145 | 7:68164002 | 0.201 | 8.66 | RL | HAVCR1 |
| 7:87107538-87300437 | 7:87131231 | 0.380 | 7.38 | CC | CCNH |
| 11:29374698-29493941 | 11:29374698 | 0.065 | 7.35 | FS | MCFD2 |
| 12:17259287-17279977 | 12:17259287 | 0.090 | 8.95 | CC | HTR2A |
| 15:11813883-12824779 | 15:11813883 | 0.315 | 7.42 | CC | Gene desert |
| 17:56698365-56747811 | 17:56698365 | 0.065 | 9.76 | CC | SUDS3 |
| 23:4387170-4419935 | 23:4419914 | 0.049 | 8.01 | CW | BMP5 |
| 28:15174368-15620173 | 28:15620173 | 0.213 | 7.58 | CW | CCDC6 |
| 28:24097580-24111037 | 28:24107275 | 0.080 | 10.24 | CC | CTNNA3 |