Schwartz 2006.
Methods | Two group randomised controlled trial with participants randomised to interim methadone maintenance treatment or a wait list control. Random assignment generated by random number table and sealed in an envelope. | |
Participants | Geographic region: USA Study setting: community methadone treatment facility. n=319, 59% male mean age =41.4 years 93% African American 62% unemployed Eligibility criteria; DSM IV heroin dependence and informed consent. Exclusions; pregnant or acute medical or psychiatric illness. |
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Interventions | Treatment: interim methadone maintenance treatment for 120 days after which entry into a comprehensive methadone treatment program if unable to gain entry before 120 days. Control: wait‐list |
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Outcomes | Entry into comprehensive methadone maintenance treatment at 4 months. Illicit drug use /self report and urinalysis. Criminal activity. | |
Notes | Mobile program that at time of study administered methadone from specially equipped recreational vehicle | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Low risk | 'table of random numbers' |
Allocation concealment? | Unclear risk | B ‐ Unclear. Sealed envelope but unclear if opaque and sequentially numbered. |
Incomplete outcome data addressed? All outcomes | Low risk | Missing outcome information balanced between groups. 95% MMT and 89% wait list located for follow up. |
Free of other bias? | Low risk | No difference between group at baseline |